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Estimating the potential malaria morbidity and mortality avertable by the US President's Malaria Initiative in 2025: a geospatial modelling analysis

Since its inception in 2005, the US President's Malaria Initiative (PMI) has played a major role in the reductions in malaria morbidity and mortality observed across Africa. With the status of PMI funding and operations currently uncertain, we aimed to quantify the impact that a fully functioning PMI would have on malaria cases and deaths in Africa during 2025. 

Citation:
Symons TL, Lubinda J, McPhail M, Saddler A, van den Berg M, Baggen H, Berman Y, Hafsia S, Jayaseelen R, Amratia P, Browne A, Cameron E, Vargas-Ruiz C, Rumisha SF, Golding N, Weiss DJ, Gething PW. Estimating the potential malaria morbidity and mortality avertable by the US President's Malaria Initiative in 2025: a geospatial modelling analysis. The Lancet. 2025;405(10496):2231-40.

Keywords:
Malaria; US President's Malaria Initiative; geospatial modelling; morbidity and mortality

Abstract:
Since its inception in 2005, the US President's Malaria Initiative (PMI) has played a major role in the reductions in malaria morbidity and mortality observed across Africa. With the status of PMI funding and operations currently uncertain, we aimed to quantify the impact that a fully functioning PMI would have on malaria cases and deaths in Africa during 2025.