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Directing immune development to curb sky-rocketing diseaseOnce upon a time it was infectious diseases like polio, measles or tuberculosis that most worried parents. With these threats now largely under control, parents face a new challenge – sky-rocketing rates of non-infectious diseases such as asthma, allergies and autism.
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Modulation of the immune system by UV radiation: More than just the effects of vitamin D?Humans obtain most of their vitamin D through the exposure of skin to sunlight
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Acute Erythemal Ultraviolet Radiation Causes Systemic Immunosuppression in the AbsenceVitamin D is synthesised by ultraviolet (UV) irradiation of skin and is hypothesized to be a direct mediator.
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Prostaglandin E2 imprints a long-lasting effect on dendritic cell progenitors in the bone marrowInjection of BM-differentiated DCs from nonchimeric mice restored the reduced immune responses of PGE2-chimeric mice.
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Immune mechanisms by which topically applied vitamin D acts as a therapeutic agentVitamin D, nutrition, diet, therapeutic agent
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Vitamin D in fetal development: Findings from a birth cohort studyBirth cohort studies provide an invaluable resource for studies of the influence of the fetal environment on health in later life.
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Dendritic cells and multiple sclerosis: Disease, tolerance and therapyMultiple sclerosis (MS) is a devastating neurological disease that predominantly affects young adults resulting in severe personal and economic impact.
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Direct infant UV light exposure is associated with eczema and immune developmentThis study is the first to demonstrate an association between greater direct UV light exposures in early infancy with lower incidence of eczema
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Vitamin D C3-epimer levels are proportionally higher with oral vitamin D supplementation compared to ultraviolet irradiation of skin in mice but not humansThe proportion of 25(OH)D3 that undergoes epimerization is greater with oral vitamin D3 supplementation than exposure to UVR in mice, but not in humans
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Sun-immune connectionExposure to ultraviolet radiation damages skin cell DNA but skin cancers develop because ultraviolet radiation also affects the immune system