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The Kids Cancer Biobank, patient-derived xenograft model development and genome-wide characterization

Raelene Nick Endersby Gottardo BSc (Hons) PhD MBChB FRACP PhD Brainchild Fellow; Co-Head, Brain Tumour Research team Co-Head, Brain Tumour Research

A data infrastructure for improving Aboriginal life pathways: the influence of health, education, child protection and justice systems over time and across generations

Incarceration represents a source of ongoing socioeconomic and health inequity between Aboriginal and non-Aboriginal populations, limiting life changes and opportunities.

LCC Flagship in Educational Equity. Using integrated administrative data to improve educational equity over the life course. UWA component - Evaluation of the Adult Migrant English Program

This project seeks to better understand the broader impacts of the AMEP on migrant outcomes.

Multigenerational disadvantage in Australia

This study aims to examine the experience of multiple disadvantages in two generations of Australian families, and how these experiences relate to the trajectories of children, the third generation.

Genetic variants in ER cofactor genes and endometrial cancer risk

Given that the transcriptional regulatory activity of estrogen receptor (ER) is modulated by its biochemical cofactors, genetic variation within the ER...

Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease

Genome-wide association studies (GWASs) have been successful at identifying single-nucleotide polymorphisms (SNPs) highly associated with common traits...

Respiratory viral pathogens associated with lower respiratory tract disease among young children

Acute lower respiratory tract infections (ALRI) commonly result in fatal outcomes in the young children of Papua New Guinea (PNG).

Fusionfinder: A software tool to identify expressed gene fusion candidates from RNA-seq data

The hallmarks of many haematological malignancies and solid tumours are chromosomal translocations, which may lead to gene fusions.

Wound healing genes and susceptibility to cutaneous leishmaniasis in Brazil

Leishmania braziliensis causes cutaneous (CL) and mucosal (ML) leishmaniasis. In the mouse, Fli1 was identified as a gene influencing enhanced wound healing...

Prevalence of and risk factors for human rhinovirus infection in healthy aboriginal and non-aboriginal western australian children

Human rhinovirus (HRV) species C (HRV-C) have been associated with frequent and severe acute lower respiratory infections and asthma in hospitalized children.