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The dramatic rise in early childhood allergic diseases indicates the specific vulnerability of the immune system to early life environmental changes.
Food allergy can have significant effects on morbidity and quality of life and can be costly in terms of medical visits and treatments.
Food allergy is mediated by a combination of genetic and environmental risk factors, potentially mediated by epigenetic mechanisms.
Investigators: Nicole Burger Assisted reproductive technologies have been associated with adverse perinatal outcomes, however subfertile women who
Debbie Susan Desiree Palmer Prescott Silva BSc BND PhD MBBS BMedSci PhD FRACP MBBS, FRACP, MPH, PhD Head, Nutrition in Early Life Honorary Research
Co-Head, The ORIGINS Project
Up to three out of every 100 babies develop cow's milk protein allergy (CMPA) in their first year of life – and this number appears to be on the rise
The current narrative surrounding children’s health and wellbeing often focuses on adversity and dysregulation with a lack of positive messaging. However, promoting protective and buffering factors may be as important as reducing adverse exposures. While the concept of flourishing is commonly applied in the context of adults, defining what flourishing means for children in current academic literature remains unclear.
Amniotic epithelial cells are fetal-derived stem cells, capable of differentiating into all three germ layers, including mature epithelial cell populations. Here, we hypothesised that the amniotic epithelium might serve as a surrogate tissue source for investigating transcriptional profiles in the respiratory epithelium of newborns.
The rates of obesity and type 1 diabetes (T1D) in children and adolescents are increasing in many settings worldwide, but data on weight gain in this group are limited in New Zealand. We examined temporal body mass index (BMI) changes and associated factors in young people with T1D in a mixed urban-rural region.