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Research
Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansionWe found transient pDC depletion during Pneumovirus infection alone predisposed to severe bronchiolitis in early life and subsequent asthma after reinfection.
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Group A streptococcal pharyngitis: Immune responses involved in bacterial clearance and GAS-associated immunopathologiesInnate and adaptive host immune responses are fundamental for defense against streptococcal pharyngitis and are central to the clinical manifestation of disease.
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Foetal growth restriction in mice modifies postnatal airway responsiveness in an age and sex-dependent mannerOur data demonstrate changes in airway responsiveness as a result of intrauterine growth restriction that could influence susceptibility to asthma development
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Exploring factors impacting early childhood health among Aboriginal and Torres Strait Islander families and communitiesThe impact of perinatal outcomes, maternal social and health outcomes and level of culturally secure service availability on the health outcomes of Western Australian Aboriginal infants and children
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Endocrine and metabolic consequences due to restrictive carbohydrate diets in children with type 1 diabetes: An illustrative case seriesThe promotion of a low carbohydrate diet in media is in contrast to published pediatric diabetes guidelines that endorse a balanced diet from a variety of foods
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Cohort profile: Pregnancy and childhood epigenetics (PACE) consortiumCurrently, DNA methylation is the most studied epigenetic phenomenon in large populations
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Investment in child and adolescent health and development: key messages from Disease Control Priorities, 3rd EditionThe realisation of human potential for development requires age-specific investment throughout the 8000 days of childhood and adolescence.
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Association of gestational age and growth measures at birth with infection-related admissions to hospital throughout childhoodChildren who were born with reduced gestational age, birthweight, and birth length have persistently increased rates of infection-related admissions to hospital until age 18 years
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Whole genome sequencing reveals extensive community-level transmission of group A Streptococcus in remote communitiesThere was evidence of extensive transmission of group A Streptococcus both within households and across the community
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Conceptualizing a quality of life framework for girls with Rett syndrome using qualitative methodsExisting quality of life scales for children in the general population or with other disabilities did not capture the QOL of children with Rett syndrome