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Genetic counseling as preventive intervention: toward individual specification of transgenerational autism riskAlthough autism spectrum disorders (ASD) are among the most heritable of all neuropsychiatric syndromes, most affected children are born to unaffected parents. Recently, we reported an average increase of 3-5% over general population risk of ASD among offspring of adults who have first-degree relatives with ASD in a large epidemiologic family sample.
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Investigating associations between birth order and autism diagnostic phenotypesBirth order effects have been linked to variability in intelligence, educational attainment and sexual orientation. First- and later-born children have been linked to an increased likelihood of an Autism Spectrum Disorder (ASD) diagnosis, with a smaller body of evidence implicating decreases in cognitive functioning with increased birth order.
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Effect of Preemptive Intervention on Developmental Outcomes Among Infants Showing Early Signs of Autism: A Randomized Clinical Trial of Outcomes to DiagnosisIntervention for individuals with autism spectrum disorder (ASD) typically commences after diagnosis. No trial of an intervention administered to infants before diagnosis has shown an effect on diagnostic outcomes to date.
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A preliminary study of fetal head circumference growth in Autism Spectrum DisorderFetal head circumference (HC) growth was examined prospectively in children with autism spectrum disorder (ASD).
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Unpacking the complex nature of the autism epidemicThe etiology of autism spectrum disorders is unknown but there are claims of increasing prevalence in many countries.
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Fetal androgen exposure and pragmatic language ability of girls in middle childhoodPrenatal exposure to testosterone has been shown to affect fetal brain maturation as well as postnatal cognition and behavior in animal studies.
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Fetal androgen exposure and pragmatic language ability of girls in middle childhood:This is the first prospective study to identify an association between early life testosterone exposure and pragmatic language difficulties in girls
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Unpacking the complex nature of the autism epidemicThis paper discusses changes in diagnostic criteria, decreasing age at diagnosis, improved case ascertainment, diagnostic substitution, and social influences.
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Adult psychosocial outcomes of children with specific language impairment, pragmatic language impairment and autismEvidence that some children also develop autistic symptomatology over time has raised suggestions that developmental language disorder...
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Cerebral dominance for language function in adults with specific language impairment or autismA link between developmental language disorders and atypical cerebral lateralization has been postulated since the 1920s, but evidence has been indirect and...