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Mechanisms of allergic disease - environmental and genetic determinants for the development of allergyEnvironmental exposures including maternal inflammation, diet, nutrient balance, microbial colonization and toxin exposures can directly and indirectly...
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Blood DNA methylation biomarkers predict clinical reactivity in food-sensitized infantsThe diagnosis of food allergy (FA) can be challenging because approximately half of food-sensitized patients are asymptomatic.
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Older maternal age and child behavioral and cognitive outcomes: A review of the literature.Although the physical consequences for offspring in utero and in the prenatal period are well known, the psychologic consequences of older motherhood for...
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25-hydroxyvitamin D3 status is associated with developing adaptive and innate immune responses in the first 6 months of lifeVitamin D status in early life has been linked to the risk of allergic disease in multiple observational studies.
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Impaired calcium influx underlies skewed T helper cell differentiation in children with IgE-mediated food allergiesReasons for Th2 skewing in IgE-mediated food allergies remains unclear. Clinical observations suggest impaired T cell activation may drive Th2 responses evidenced by increased atopic manifestations in liver transplant patients on tacrolimus (a calcineurin inhibitor). We aimed to assess differentiation potential, T cell activation and calcium influx of naïve CD4+ T cells in children with IgE-mediated food allergies.
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Early MovesThe Early Moves study is investigating whether a baby’s early movements can predict difficulties with learning (known as cognitive impairment) later in childhood.
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Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebioticsIn December 2016, a panel of experts was convened by the International Scientific Association for Probiotics an Prebiotics to review the scope of prebiotic.
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Project earthrise: Proceedings of the ninth annual conference of in vivo planetary healthThe “Earthrise” photograph, taken on the 1968 Apollo 8 mission, became one of the most significant images of the 20th Century. It triggered a profound shift in environmental awareness and the potential for human unity—inspiring the first Earth Day in 1970. Taking inspiration from these events 50 years later, we initiated Project Earthrise at our 2020 annual conference of inVIVO Planetary Health.
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The association of mobile touch screen device use with parent-child attachment: a systematic reviewMobile touch screen devices (smartphones and tablet computers) have become an integral part of many parents’ and children’s lives, with this interaction linked to physical, mental and social outcomes. Despite the known importance of parent-child attachment, evidence on the association between device use and attachment was yet to be reviewed.
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Health-related behaviours and weight status of expectant fathersLittle attention has been given to the health status and lifestyle behaviours of expectant fathers. This study aimed to examine health-related variables in a cohort of expectant fathers to identify potential focus areas for interventions designed to optimise health and wellbeing outcomes in this group.