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This study contributes to our understanding of the genetic diversity of NMC, an important step towards finding therapeutic targets for a disease that is...

Brain tumors presenting in infancy, especially during the first 6 months of life.

Acute Lymphoblastic Leukemia (ALL) occurring in the first year of life is rare.

Genotyping has become more cost-effective and less invasive with the use of buccal cell...

Medulloblastoma (MB) is the most common type of malignant childhood brain tumour.

The hallmarks of many haematological malignancies and solid tumours are chromosomal translocations, which may lead to gene fusions.

Childhood brain tumors (CBT) are the leading cause of cancer death in children; their risk factors are still largely unknown.

This chapter summarizes recent advances in diffuse intrinsic pontine glioma and potential novel therapies

We provide evidence that targeting leukemia-induced bone loss is a therapeutic strategy for pre-B ALL

Here we report that CHAF1B is required for normal hematopoiesis while its overexpression promotes leukemia