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Research

The Human Phenotype Ontology in 2021

The Human Phenotype Ontology was launched in 2008 to provide a comprehensive logical standard to describe and computationally analyze phenotypic abnormalities found in human disease. The HPO is now a worldwide standard for phenotype exchange. The HPO has grown steadily since its inception due to considerable contributions from clinical experts and researchers from a diverse range of disciplines. Here, we present recent major extensions of the HPO for neurology, nephrology, immunology, pulmonology, newborn screening, and other areas.

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Inequalities in child development at school entry: A repeated cross-sectional analysis of the Australian Early Development Census 2009-2018

Australia is the only developed country to consistently undertake a developmental census of its children nationwide. The repeated collection of the Australian Early Development Census (AEDC) has provided an unprecedented opportunity to examine the prevalence of developmental vulnerability across Australia's states and territories, the socio-economic distribution of developmental vulnerability across jurisdictions, and how these distributions might have changed over time.

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Measuring early childhood development in multiple contexts: the internal factor structure and reliability of the early Human Capability Index in seven countries

Findings support the aims of the early Human Capability Index in being adaptable and applicable for use within a range of low and middle income countries

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Does Child Care in the First Year of Life Pose a Risk for Concurrent and Future Ear Infections?

The longitudinal analyses found no evidence of increased (or decreased) long-term risk of ear infections in subsequent waves associated with attending a child care centre

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Lao PDR. Early childhood education project Snapshot one: project background and baseline data demographics

This snapshot describes demographic information of the 7,520 children in the baseline sample, including where and how they live.

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Investing in School Readiness : An Analysis of the Cost-Effectiveness of Early Childhood Education Pathways in Rural Indonesia

This paper presents evidence on the cost-effectiveness of early childhood education pathways in rural Indonesia

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Exploring change in the Australian version of the Early Development Instrument

Calculating a critical difference for the percentage of children who are “at risk” and “on track” in addition to the children who are developmentally “vulnerable”

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Investigation of the Cross-National Equivalence of a Measurement of Early Child Development

This research paper reports on the results of investigating measurement invariance of the Early Development Instrument (EDI) in two South-Asian countries.

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The impact of maternal gestational stress on motor development in late childhood and adolescence: A longitudinal study

The purpose of this article is to investigate whether the number and timing of stressors experienced during pregnancy impacted longterm motor development at...

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What factors contribute to positive early childhood health and development in Australian Aboriginal children? Protocol for a population-based cohort study

Empirical evidence identifying the key drivers of positive early childhood development in Aboriginal children, and supportive features of local communities...