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Epigenome-Wide Association Study of Thyroid Function Traits Identifies Novel Associations of fT3 With KLF9 and DOT1LThe aim is to identify novel associations between fT3, fT4, and TSH and differentially methylated positions (DMPs) in the genome in subjects from 2 Australian cohorts. We performed an epigenome-wide association study (EWAS) of thyroid function parameters and DNAm using participants from Brisbane Systems Genetics Study and the Raine Study.
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Two decades of increasing incidence of childhood-onset type 2 diabetes in Western Australia (2000–2019)This retrospective population‐based study aimed to determine the incidence of type 2 diabetes from 2012 to 2019 in Western Australian youth aged under 16 years, and to examine temporal trends between 2000 and 2019, using data from the Western Australian Children’s Diabetes Database (WACDD). The data extracted for eligible patients diagnosed with type 2 diabetes, according to standard criteria, included diagnosis year, age, sex and self‐reported Aboriginal or Torres Strait Islander status.
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Reduced prevalence of impaired awareness of hypoglycemia in a population-based clinic sample of youth with type 1 diabetesThe aim of this study was to determine the change in prevalence of Impaired awareness of hypoglycemia in adolescents with Type 1 diabetes
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Sub-erythemal ultraviolet radiation reduces metabolic dysfunction in already overweight miceExposure to sunlight may limit cardiometabolic risk.
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Minimizing Hypoglycemia in DiabetesHypoglycemia caused by treatment with a sulfonylurea, a glinide, or insulin coupled with compromised defenses against the resulting falling plasma glucose...
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Questionnaires Measuring Physical Activity in Clinical Pediatric Populations: A Systematic ReviewRegular physical activity (PA) is a cornerstone therapy for many childhood chronic health conditions, and questionnaires offer a simple method for monitoring PA and identifying children who do not meet clinical practice guidelines. The purpose of this systematic review is to determine which questionnaires are most efficacious for assessing PA in children with chronic health conditions.
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ISPAD Clinical Practice Consensus Guidelines 2022: Definition, epidemiology, and classification of diabetes in children and adolescentsCitation: Libman I, Haynes A, Lyons S, Pradeep P, Rwagasor E, et al. ISPAD Clinical Practice Consensus Guidelines 2022: Definition, epidemiology, and
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Maternal smoking during pregnancy and the risk of childhood type 1 diabetes in Western AustraliaThe aim of this study was to investigate the association between maternal smoking during pregnancy and type 1 diabetes in the offspring, using complete...
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Contribution of an intrinsic lag of continuous glucose monitoring systemsCurrent continuous glucose monitoring (CGM) systems measure glucose levels in the interstitial fluid to estimate blood glucose concentration.
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Type 2 Diabetes in Indigenous Australian childrenRates of type 2 diabetes are higher among Indigenous than non-Indigenous Australian children and adolescents.