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Research

Prevalence and predictors of vitamin D deficiency in a nationally representative sample of Australian adolescents and young adults

Vitamin D deficiency is a public health concern worldwide. Maintaining vitamin D sufficiency during growth periods is essential. We aimed to determine the prevalence and predictors of vitamin D deficiency in Australian adolescents and young adults.

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Sun-immune connection

Exposure to ultraviolet radiation damages skin cell DNA but skin cancers develop because ultraviolet radiation also affects the immune system

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Vitamin D C3-epimer levels are proportionally higher with oral vitamin D supplementation compared to ultraviolet irradiation of skin in mice but not humans

The proportion of 25(OH)D3 that undergoes epimerization is greater with oral vitamin D3 supplementation than exposure to UVR in mice, but not in humans

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Ultraviolet irradiation of skin alters the faecal microbiome independently of vitamin D in mice

Skin exposure to ultraviolet radiation alters the faecal microbiome, and further investigations to explore the implications of this in health and disease are warranted

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Analytical bias in the measurement of plasma 25-hydroxyvitamin D concentrations in infants

To our knowledge, this is the first study to show that the reported 25(OH)D concentration may be influenced by both age and assay type

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Calcium and Vitamin D for obesity: review of randomized controlled trials

Obesity often coexists with low calcium intake and vitamin D insufficiency.

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Low-dose UV radiation before running wheel access activates brown adipose tissue

When combined with physical activity, low-dose UVR may more effectively limit adiposity and modulate metabolic and immune pathways in iBAT

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House dust mite induced lung inflammation does not alter circulating vitamin D levels

We hypothesized that allergic inflammation decreases the level of circulating 25(OH)D and tested this using a mice model of house dust mite (HDM) induced...

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Sun exposure and vitamin D status as northeast asian migrants become acculturated to life in Australia

Targeted public health approaches are required to manage the high prevalence of vitamin D deficiency in migrants retaining a traditional lifestyle

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Seasonal variation of relapse rate in multiple sclerosis is latitude dependent

We demonstrate a latitude-dependent relationship between seasonal UVR trough and relapse onset probability peak independent of location-specific UVR levels