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This study will investigate the why disease is worse in infants and how early life viral infection impacts the developing immune system.

This is a strategic “pilot” project in which we are seeking basic information on the immune cell content of gestational tissues.

This project investigates how different populations of cells within the respiratory tract immune system are altered during a viral infection.

Head, Pregnancy and Early Life Immunology

Airway epithelial cells act through multiple mechanisms to function as an important component of the pulmonary defence strategy that is crucial...

Atopic asthma, which is at its highest prevalence during childhood/young adulthood, represents the main focus of this review.

Airways hyperresponsiveness (AHR) is one of the major clinical features of allergic airways disease including allergic asthma

A significant proportion of chronic obstructive pulmonary disease exacerbations are strongly associated with rhinovirus infection (HRV). In this study, we combined long-term cigarette smoke exposure with HRV infection in a mouse model.

The lack of a consensus definition of neonatal sepsis and a core outcome set proves a substantial impediment to research that influences policy and practice relevant to key stakeholders, patients and parents.

Dysbiosis refers to a reduction in microbial diversity, combined with a loss of beneficial taxa, and an increase in pathogenic microorganisms. Dysbiosis of the intestinal microbiota can have a substantial effect on the nervous and immune systems, contributing to the onset of several inflammatory diseases.