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Immune-Microbiota Interactions: Dysbiosis as a Global Health IssueThe implications of the microbiome extend to virtually every branch of medicine, biopsychosocial and environmental sciences
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An international survey of cerebral palsy registers and surveillance systemsThese findings will facilitate harmonization of data and collaborative research efforts, which are so necessary on account of the heterogeneity and...
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Maternity-care: measuring women’s perceptionsDevelopment of an instrument to assess women's perception of their entire maternity-care experience
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Comparing risks of cerebral palsy in births between Australian Indigenous and non-Indigenous mothersIndigenous infants have a higher risk of CP than non-Indigenous infants, especially postneonatal CP.
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Longer-term increased cortisol levels in young people with mental health problemsHair segment analyses revealed longer-term increased levels of cortisol in the past 3 months in early mental health problems
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Sleep-disordered breathing in Australian children with Prader-Willi syndrome following initiation of growth hormone therapyIn children with Prader-Willi syndrome (PWS), growth hormone (GH) improves height and body composition; however, may be associated with worsening sleep-disordered breathing (SDB). Some studies have reported less SDB after GH initiation, but follow-up with polysomnography is still advised in most clinical guidelines.
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Variation in treatment preferences of pulmonary exacerbations among Australian and New Zealand cystic fibrosis physiciansDespite advances in cystic fibrosis (CF) management and survival, the optimal treatment of pulmonary exacerbations remains unclear. Understanding the variability in treatment approaches among physicians might help prioritise clinical uncertainties to address through clinical trials.
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Streptolysins are the primary inflammasome activators in macrophages during Streptococcus pyogenes infectionGroup A Streptococcus (GAS) is a Gram-positive bacterial pathogen that causes an array of infectious diseases in humans. Accumulating clinical evidence suggests that proinflammatory interleukin (IL)-1beta signaling plays an important role in GAS disease progression.
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The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replicationWe report a role for the mitochondrial single-stranded DNA binding protein (mtSSB) in regulating mitochondrial DNA (mtDNA) replication initiation in mammalian mitochondria. Transcription from the light-strand promoter (LSP) is required both for gene expression and for generating the RNA primers needed for initiation of mtDNA synthesis.
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The association of mobile touch screen device use with parent-child attachment: a systematic reviewMobile touch screen devices (smartphones and tablet computers) have become an integral part of many parents’ and children’s lives, with this interaction linked to physical, mental and social outcomes. Despite the known importance of parent-child attachment, evidence on the association between device use and attachment was yet to be reviewed.