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Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosisIdiopathic pulmonary fibrosis (IPF) is a fatal disease that is unresponsive to current therapies.
Research
Identification of suitable endogenous control genes for microRNA expression profiling of childhood medulloblastoma and human neural stem cellsMedulloblastoma (MB) is the most common type of malignant childhood brain tumour.
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TLR3 and RIG-I gene variants: Associations with functional effects on receptor expression and responses to measles viruMeasles virus causes severe morbidity and mortality, despite the availability of measles vaccines. Successful defence against viral pathogens requires early...
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Progression of early structural lung disease in young children with cystic fibrosis assessed using CTCross-sectional studies implicate neutrophilic inflammation and pulmonary infection as risk factors for early structural lung disease in infants and young...
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Increased mortality among Indigenous persons during and after release from prison in New South WalesThe objective of this study was to estimate the overall and cause specific mortality of Aboriginal offenders in New South Wales (NSW), Australia.
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Parental occupational exposure to engine exhausts and childhood brain tumorsChildhood brain tumors (CBT) are the leading cause of cancer death in children; their risk factors are still largely unknown.
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Small macrophages are present in early childhood respiratory diseaseRecently, an established "small macrophage" phenotype has been observed in the sputum of patients with CF and COPD. However, little is known about the...
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Defective aeroallergen surveillance by airway mucosal dendritic cells as a determinant of riskA hallmark of atopic asthma is development of chronic airways hyper-responsiveness (AHR) that persists in the face of ongoing exposure to perennial...
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Pulmonary diffusing capacity in healthy Caucasian childrenPrevious studies of pulmonary diffusing capacity in children differed greatly in methodologies; numbers of subjects evaluated, and were performed prior to...
Research
Heavy prenatal alcohol exposure and increased risk of stillbirthThe objective was to investigate the association between heavy prenatal alcohol exposure and stillbirth.