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Kids researchers using real tonsils in quest to develop new Strep A vaccineA new study underway at the Wesfarmers Centre of Vaccines and Infectious Diseases, based at The Kids Research Institute Australia, is deliberately infecting tonsils with Strep A in the laboratory to test a range of potential vaccine candidates.
News & Events
Friendly bacteria reduces flu symptoms and ear infections in miceResearch reveals that friendly bacteria may help reduce flu symptoms, offering new insights into potential treatments and enhancing our understanding of immune health.
News & Events
Australia on the cusp of one-shot meningococcal protectionA life-saving meningococcal vaccine covering all five common strains of the deadly disease could soon be available thanks to vital research demonstrating the safety and effectiveness of a combination Men ABCWY vaccine.
News & Events
Ear Explorers shows latest video technology helps ear disease diagnosisFindings from The Kids Research Institute Australia’s ‘Ear Explorers’ real-life research project undertaken as part of the 2019 Telethon weekend, found short videos were more helpful than photos when making a diagnosis.
Research
Acellular Pertussis Vaccine Given in the Week After Birth Does Not Impair Antibody Responses to Later Childhood DosesA birth acellular pertussis vaccine may be a valuable alternative for immunity against infant pertussis when a pregnancy pertussis vaccine has not been administered. We assessed whether a birth dose may impair immunoglobulin G (IgG) responses to childhood pertussis boosters.
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Multi-million-dollar investment in child health to support vital researchFour The Kids Research Institute Australia researchers have received prestigious fellowships and four significant cohort studies led or co-led by The Kids have received key grants under two new funding programs supported by the State Government’s Future Health Research and Innovation (FHRI) Fund.
Research
COVID-19 in Ethiopia: A geospatial analysis of vulnerability to infection, case severity and deathCOVID-19 has caused a global public health crisis affecting most countries, including Ethiopia, in various ways. This study maps the vulnerability to infection, case severity and likelihood of death from COVID-19 in Ethiopia. Thirty-eight potential indicators of vulnerability to COVID-19 infection, case severity and likelihood of death, identified based on a literature review and the availability of nationally representative data at a low geographic scale, were assembled from multiple sources for geospatial analysis. Geospatial analysis techniques were applied to produce maps showing the vulnerability to infection, case severity and likelihood of death in Ethiopia at a spatial resolution of 1 km×1 km.
Research
Protocol for establishing a core outcome set for evaluation in studies of pulmonary exacerbations in people with cystic fibrosisPulmonary exacerbations are associated with increased morbidity and mortality in people with cystic fibrosis (CF). There is no consensus about which outcomes should be evaluated in studies of pulmonary exacerbations or how these outcomes should be measured.
Research
Harmonizing Surveillance Methodologies for Group A Streptococcal DiseasesGroup A Streptococcus (Strep A) is responsible for a significant global health and economic burden. The recent prioritization of Strep A vaccine development by the World Health Organization has prompted global research activities and collaborations. To progress this prioritization, establishment of robust surveillance for Strep A to generate updated regional disease burden estimates and to establish platforms for future impact evaluation is essential.
Research
Evidence of maternal transfer of antigen-specific antibodies in serum and breast milk to infants at high-risk of S. pneumoniae and H. influenzae diseaseChildren in low-mid income countries, and First Nations children in high-income countries, experience disproportionately high rates of Streptococcus pneumoniae and Haemophilus influenzae infections and diseases including pneumonia and otitis media.