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Inflammatory mediators from peripheral tissues may control dendritic cell (DC) development in the bone marrow.
The anti-inflammatory actions of IL-4 in activated human monocytes may reflect transcriptional regulation of genes involved in TLR signaling pathways.
There is considerable debate about the benefits of vitamin D supplementation for multiple sclerosis, allergic asthma, and type 1 diabetes.
Humans obtain most of their vitamin D through the exposure of skin to sunlight
In healthy individuals, deep inspiration produces bronchodilation and reduced airway responsiveness, which may be a response of the airway wall to mechanical...
Neutrophils are the most abundant immune cell in circulation. However, due to a number of technical challenges for researchers, including the neutrophil's short lifespan and difficulties with preservation, they are often discarded during blood processing and thus ignored in cohort studies. As such, the contribution of neutrophils to disease and their involvement in disease mechanisms is less explored compared with other immune cell types.
Vitamin D may be essential for restricting the development and severity of allergic diseases and asthma, but a direct causal link between vitamin D...
In experimental models, both vitamin D3-dependent and vitamin D3-independent pathways have been implicated in the mechanisms of UVR-induced systemic...
Despite considerable advances, the exact mechanism whereby UVR can lead to changes in immune responses is not entirely clear at present, and no...
In this chapter, evidence for and evidence against the involvement of vitamin D in the immunoregulatory properties of UV radiation is presented.