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This article looks at the clinical implications of the research into microbial exposure & protection against asthma.
Asthma is more common in childhood than in adulthood and is more correctly thought of as a syndrome than as a discrete condition.
Food allergy (FA) affects 2%-10% of US children and is a growing clinical and public health problem.
The expression pattern of FcεRI on DC and basophils differentiates asthmatic from non-asthmatic atopic children
Dysregulated expression of IFN-dependent pathways after respiratory viral infections is a defining immunophenotypic feature of AVB-susceptible infants
Pregnancy is associated with an alternatively activated phenotype of alveolar macrophage before infection
This protocol adapted an experimental animal model of disease for sensitization to ovalbumin during the immediate post-weaning period beginning at 21 days of age
Type 1 and 3 interferon response capacity appears strongly developmentally constrained at birth
There is a marked shift in innate and adaptive immune responses in Chinese immigrants after living in a Western environment for several years
Our findings suggest that the proportion of degranulated basophils can also be associated with recurrent exacerbations