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Haematological malignancies, although a broad range of specific disease types, continue to show considerable overlap in classification, and patients are...
Connective tissue growth factor (CTGF/CCN2) has been shown previously to be aberrantly expressed in a high proportion of paediatric precursor B cell acute...
This novel approach aimed to prevent inflated hazard ratios arising from reverse causation, and allow identification of associations beyond those already...
Results indicated a strong familial basis of melanoma, with the higher than expected hazard ratio observed likely to reflect early-age at onset cases in this...
There are indications that risk factors for BCC may differ according to the anatomic site of the tumour but this is not well understood.
Recent research suggests that maternal folic acid supplementation is associated with a reduced risk of childhood brain tumors (CBT); polymorphisms in folate...
One of the great success stories of modern medicine is undoubtedly the remarkable improvement in outcome for childhood cancer, achieved through the work of...
Our results identify a pretreatment tumor microenvironment that predicts response to immune checkpoint blockade, which can be therapeutically attained
In this study, we investigate the in vivo synergy between romidepsin and cytarabine
These findings suggest that tumor cells employ multiple epigenetic and genetic mechanisms to evade immune control