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The effect of diesel exhaust exposure on blood-brain barrier integrity and function in a murine modelEpidemiological studies indicate that exposure to diesel exhaust (DE) is associated with vascular-based disorders.
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Emerging Early Life Environmental Exposures and Lung DevelopmentIn this review article we systematically summarize the evidence for an impact on lung development of 1) maternal ingestion of arsenic contaminated drinking...
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Boosting airway T-regulatory cells by gastrointestinal stimulation as a strategy for asthma controlThe hallmark of atopic asthma is transient airways hyperresponsiveness (AHR) preceded by aeroallergen-induced Th-cell activation.
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Genome Sequences of Two Lytic Staphylococcus aureus Bacteriophages Isolated from WastewaterTwo lytic double-stranded DNA (dsDNA) bacteriophages, belonging to the family Herelleviridae, were isolated from wastewater in Western Australia. Biyabeda-mokiny 2 appears to belong to the genus Kayvirus, and Koomba-kaat 1 to Silviavirus.
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The effects of acamprosate on maternal and neonatal outcomes in a mouse model of alcohol use disordersDespite the teratogenic effects of alcohol, little is known about the safety of pharmacotherapies such as acamprosate for the treatment of alcohol use disorders in pregnancy. The aims of this study were to investigate, in a mouse model, the effects of maternally administered acamprosate on maternal and neonatal health, offspring neurodevelopment and behaviour, as well as examine whether acamprosate reduces the neurological harm associated with alcohol consumption in pregnancy.
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Quantifying airway remodelling for research or clinical purposes: How should we normalize for airway size?Citation: Donovan GM, Wang KCW, Elliot JG, James AL, Noble PB. Quantifying airway remodelling for research or clinical purposes: How should we
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Intrauterine growth restriction affects diaphragm function in adult female and male miceSex and intrauterine growth restriction independently affect diaphragm contraction in adult mice without changes in structure
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Alcohol pharmacotherapy dispensing trends in Australia between 2006 and 2023This study aimed to investigate acamprosate and naltrexone dispensing patterns in Australia.
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Stiffness Mediated-Mechanosensation of Airway Smooth Muscle Cells on Linear Stiffness Gradient HydrogelsIn obstructive airway diseases such as asthma and chronic obstructive pulmonary disease (COPD), the extracellular matrix (ECM) protein amount and composition of the airway smooth muscle (ASM) is often remodelled, likely altering tissue stiffness. The underlying mechanism of how human ASM cell (hASMC) mechanosenses the aberrant microenvironment is not well understood.
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Fragranced consumer products: effects on asthmatic AustraliansMost asthmatics would prefer workplaces, healthcare facilities, and environments that are fragrance-free, which could help reduce adverse effects